Ala I Sharara,* Elie Aoun,* Suzanne Koussa, ^† Adlette Inati ^† and Ali Taher*^,†

Acute infection with hepatitis C virus (HCV) is rarely recognized in children, except in the setting of an outbreak. Screening of blood and blood products has virtually eliminated the risk of HCV acquisition from transfusions and perinatal transmission has become the leading route of new HCV infection in children.
There are no reports on the type or duration of therapy of acute HCV in children. Herein, we report a child with thalassemia major who developed transfusion-associated acute hepatitis C treated successfully with weight-based dosing of peginterferon α-2b.