GeneID: 137

Description:
OLFM5P is classified as a pseudogene and member of the family of olfactomedins. The olfactomedin domain-containing proteins appear to facilitate protein-protein interactions, sometimes in conjuction with extracellular matrix components, and are proposed to play essential roles in development and cell differentiation. Members of this family are implicated in the process of olfaction, neurosecretion and neural development. Polymorphisms in the OLFM5P gene associated with HbF levels in sickle cell patients.

Synonyms: LOC101927763

Comments:
N/A

Number of entries/variants: 1

1. Karavanich CA, Anholt RR, Molecular evolution of olfactomedin., Mol. Biol. Evol. , 15(6), 718-26, 1998 PubMed
2. Uda M, Galanello R, Sanna S, Lettre G, Sankaran VG, Chen W, Usala G, Busonero F, Maschio A, Albai G, Piras MG, Sestu N, Lai S, Dei M, Mulas A, Crisponi L, Naitza S, Asunis I, Deiana M, Nagaraja R, Perseu L, Satta S, Cipollina MD, Sollaino C, Moi P, Hirschhorn JN, Orkin SH, Abecasis GR, Schlessinger D, Cao A, Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia., Proc. Natl. Acad. Sci. U.S.A. , 105(5), 1620-5, 2008 PubMed
3. Anholt RR, Olfactomedin proteins: central players in development and disease., Front Cell Dev Biol , 2(0), 6, 2014 PubMed