Frequently Asked Questions - IthaMaps database

FAQs - IthaMaps database

IthaMaps is a database that stores and organiases information about the epidemiology of haemoglobinopathies and illustrates and compares the data on a map. 

IthaMaps provides the following information:

  1. Information of haemoglobinopathy-related healthcare policies in each country, including screening and prevention programmes, existence and availability of electronic parient registries and dedicated treament centres etc.
  2. Information on the status of major haemoglobinopathies in each country, including prevalence and incidence of thalassaemias and sickle-cell disease.
  3. Relative allele frequencies of specific mutations in each country, with detailed information about each study (sample size, ethnic groups, specific geographical areas etc.). Where possible, a more detailed region-specific presentation of the frequencies is provided within the country. 

IthaGenes is curated by The IthaGenes Curation Team, which includes the following scientists:

  • Dr. Petros Kountouris
  • Dr. Carsten W Lederer
  • Dr. Coralea Stephanou
  • Dr. John Old
  • Dr. Marina Kleanthous

The curation is also facilitated with the contribution of members of the ITHANET Advisory Committee

The Committee Members:

Erol Baysal Alex Felice
Jan Traeger Synodinos Ali Taher
Maria Sitarou Yeshim Aydinok
Roberto Gambari Swee Lay Thein
Suthat Fucharoean Stefano Rivella
Lila Yannaki Cornelis L. Hartveld
Petr Holub John Old
Michael Angastiniotis Marina Kleanthous
Jim Vadolas Aurelio Maggio
Soteroulla Christou  

Like IthaGenes, the updating of IthaMaps is based on published literature the curation team receives every week from PubMed using the following search query: "thalassemia[tiab] OR thalassaemia [tiab] OR hemoglobin [tiab] OR haemoglobin [tiab] OR sickle-cell [tiab] OR hemoglobinopathies [tiab] OR haemoglobinopathies [tiab]".  The list of publications is manually filtered by the IthaMaps Curation Team to identify new epidemiological information about haemoglobinopathies.  The new data are subsequently added into the database. Information on healthcare policies are not always available in piblished articles, so further annotation is achieved with personal communication with local experts and from information from presentations and reports.

A search form is available at the top of IthaMaps page. The user can search for a specific country or for information about healthcare policies, haemoglobinopathy status and relative frequencies of specific mutations. Additional options appear based on the selection. Healthcare policies and major haemoglobinopathies status are available for the world map only, while country selection and specific mutation frequencies can be combined. In the latter case, region-specific information are displayed on the country map, if available. Information on the frequencies of specific muations can be customised based on the selection of country- or region-specific representation, sample size and the type of statistics to be used for the illustration (average values, minimum or maximum).

IthaMaps uses the HighMaps javascript library for displaying the epidemiological information, which provides exporting functionality. The resulting map after any custom search can be exported in a variety of formats and be used for your presentations or for other purposes. To export a map, you can use the button at the top right of the map.

Please use the Contact Form to report any correction or new content for IthaMaps.