Sickle cell C disease

a disease resulting from abnormal sickle-shaped erythrocytes (containing hemoglobin C and hemoglobin S) which appear in response to a lowering of the partial pressure of oxygen; characterized by anemia, crises due to hemolysis or vascular occlusion, chronic leg ulcers and bone deformities, and infarcts of bone or of the spleen See hemoglobin C, hemoglobin S