Myelodysplasia

(MDS); a range of disorders associated with ineffective hematopoiesis, often leading to cytopenia and requirement for chronic blood transfusions

Description
MDS is generally caused by differentiation disorders of blood-cell precursors, and is therefore associated with an amplification of undifferentiated cells in the bone marrow, predisposing affected individuals to leukemia. Syn myelodysplastic syndrome