Hemochromatosis

a disorder of iron metabolism characterized by excessive absorption of ingested iron, saturation of iron-binding protein, and deposition of hemosiderin in tissue, particularly in the liver, pancreas, and skin

Description
Hemochromatosis brings with it cirrhosis of the liver, diabetes (bronze diabetes), bronze pigmentation of the skin and, possibly, eventual heart failure. Importantly for hemoglobinopathies, hemochromatosis can also result from administration of large amounts of iron orally or by injection, or by prolonged blood transfusion therapy.