Blood coagulation

a complex process preventing blood loss from damaged blood vessels (hemostasis)

Description
It is intiated by the attachment of platelets to a wound site (primary hemostasis} and followed by a cascade of coagulation factors that form fibrin strands which reinforce the initial hemostatic platelet plug. Coagulation disorders can lead to increased hemorrhage (e.g. in hemophilia) or thrombosis and embolism.