Lymphocyte-mediated cytotoxicity

the toxic or lytic activity of lymphocytes, which may or may not be mediated by antibodies

Description
Cytotoxic T lymphocytes may cause lysis of cells by production of cytolytic proteins such as perforin. B cells may cause lysis of cells by antibody-complement binding to a target cell. Natural killer cells are cytotoxic without prior sensitization. See antibody-dependent, cell-mediated cytotoxicity, lymphocyte