GeneID: 410

Names

Common Name:	WWOX	Type:	Gene
Chromosome:	16 (NC_000016.10)	Locus:	NG_011698.1 (WWOX)
HUGO Symbol:	WWOX	Full Name:	WW domain containing oxidoreductase
Exons:	9	Introns:	8

Description:
The WWOX gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. Acts as a tumor suppressor and plays a role in apoptosis. Associated with haematopoietic malignancies. Genetic variance in WWOX associated with F-cell levels in sickle cell anaemia.

Synonyms: FOR , WOX1 , EIEE28 , FRA16D , SCAR12 , HHCMA56 , PRO0128 , SDR41C1 , D16S432E

Comments:
N/A

Number of entries/variants: 1

External Links

NCBI Gene	UniProtKB
PDB	HGNC
OMIM

IthaScore

Publications / Origin

Bhatnagar P, Purvis S, Barron-Casella E, DeBaun MR, Casella JF, Arking DE, Keefer JR, Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients., J. Hum. Genet. , 56(4), 316-23, 2011

Created on 2020-10-15 14:56:44, Last reviewed on (Show full history)

A/A	Date	Curator(s)	Comments
1	2020-10-15 14:56:44	The IthaGenes Curation Team	Created

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