GeneID: 44
Names
Common Name: | SMAD3 | Type: | Gene |
---|---|---|---|
Chromosome: | 15 (NC_000015.10) | Locus: | NG_011990.1 (SMAD3) |
HUGO Symbol: | SMAD3 | Full Name: | SMAD family member 3 |
Exons: | 9 | Introns: | 8 |
Description:
SMAD3 is a member of the SMAD family of proteins, which act as transcriptional regulators in the transforming growth factor β (TGFβ) signalling pathway. TGFβ/SMAD3 signalling may play a role in the regulation of carcinogenesis. Polymorphisms in the SMAD3 gene associated with HbF levels in African American sickle cell patients.
Synonyms: HsT17436 , JV15-2
Comments:
N/A
Number of entries/variants: 2
Sequence Viewer
Note: The NCBI Sequence Viewer is not installed on the ITHANET servers but it is embedded in this page from the NCBI.
Therefore, IthaGenes has no responsibility over any temporary unavailability of the service.
In such a case, please Refresh the page or retry at a later stage.
Publications / Origin
- Massagué J, Seoane J, Wotton D, Smad transcription factors., Genes Dev. , 19(23), 2783-810, 2005 PubMed
Created on ,
Last reviewed on 2016-04-25 14:57:04 (Show full history)
A/A | Date | Curator(s) | Comments |
---|---|---|---|
1 | The IthaGenes Curation Team | Created | |
2 | 2016-04-25 14:51:01 | The IthaGenes Curation Team | Reviewed. |
3 | 2016-04-25 14:57:04 | The IthaGenes Curation Team | Reviewed. |
Disclaimer: The information on this website is provided as an information resource only
and must not to be used as a substitute for professional diagnosis and treatment.
The ITHANET Portal and IthaGenes are not responsible or liable for any advice, course of treatment,
diagnosis or any other information, services or products that an individual obtains through this website.
IthaGenes was last updated on 2024-03-28 09:17:36