Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
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General information for Bahrain
Bahrain |
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Haemoglobinopathy-specific healthcare policy information for Bahrain
Healthcare policy | Comment/Info | Reference | |
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Prevention programme: | Yes (National) | Based on premarital screening. Mandatory since 2004. | [PMID: 23224852] |
SCD newborn screening: | Yes (National) | NBS for haemoglobinopathies since May 2007; includes SCD. | [PMID: 22550494] |
Prenatal screening: | Yes (National) | Service is available for β-thalassaemia. | [PMID: 11773575] |
Antenatal screening: | Yes (National) | Since 1992. | [PMID: 29751732] |
Haemoglobinopathies patient registry: | Yes (Regional) | Centre-based; Primary health care center registers of SCD patients [Source: AlSaleh A. et al, Bahrain Medical Bulletin, Vol. 43, No. 2, June 2021] | |
Dedicated treatment centres: | Yes (National) | From: PGPR, Global Sickle Cell Disease Network. | |
Blood transfusion availability: | Yes (National) | From: PGPR, Global Sickle Cell Disease Network. | |
MRI facilities: | Yes (National) | From: PGPR, Global Sickle Cell Disease Network. | |
Patient associations: | Yes (National) | Bahrain National Hereditary Anemia Society | [PMID: 22550494] |
Genetic counselling: | Yes (National) | Offered as part of mandatory premarital screening program. | [PMID: 11773575] |
Prevalence and incidence of major haemoglobinopathies in Bahrain
Haemoglobinopathy | Comment/Info | Reference | |
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Prevalence of β-thalassaemia carriers: | 3.5 % of the population | [PMID: 24672827] | |
Prevalence of sickle cell disease carriers: | 11 % of the population | Up to 16.4% in other reports. | [PMID: 24672827] |
Prevalence of α-thalassaemia carriers: | 24.3 % of the population | [PMID: 23224852] | |
Prevalence of Hb C carriers: | 0 % of the population | [PMID: 15751927] | |
Expected incidence of β-thalassaemia: | 4 expected affected births/year | [PMID: 24672827] | |
Expected incidence of sickle cell disease: | 61 expected affected births/year | [PMID: 24672827] | |
Incidence of sickle cell disease: | 59 affected births/year | Median value estimated using statistical model and demographic data. | [PMID: 23103089] |
Known β-thalassaemia patients: | 300 patients | [PMID: 24672827] | |
Known sickle cell disease patients: | 600 patients | [PMID: 24672827] |
Global Burden of Disease data for Bahrain
Migration data for Bahrain
Mutation frequencies in Bahrain
Overview (most frequent mutations with their observed average values and range)
β-locus
IVS I [3' end] (-25 bp): 36.1 % | CD 39 CAG>TAG [Gln>STOP]: 24.2 % |
IVS I-5 (G>C): 16.7 % | IVS II-1 G>A: 6.1 % |
Detailed mutation frequencies
Entry ID | Locus | Region | Ethnic Group | Population Type | Sample Size | Study period (from) | Study period (to) | Reference | Comments | |
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23259 | β-locus | Manama | Bahraini | Carriers and Patients | 66 | 1998 | 9668568 | Frequencies are shown for beta-globin gene mutations. Study samples were acquired from the Salmaniya Medical Centre, Manama. |
Organisations in Bahrain
Organisations in Bahrain are currently not available
Microattributions
No microattibutions were provided for Bahrain. Please contact us, if you are willing to review existing information or provide new data.
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Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.