Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
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General information for Canada
Canada |
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Haemoglobinopathy-specific healthcare policy information for Canada
Healthcare policy | Comment/Info | Reference | |
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Prevention programme: | Yes (Regional) | Based on premarital/preconception screening. | [PMID: 19038079] |
SCD newborn screening: | Yes (Regional) | Universal. Carried out in 8 Canadian provinces. From: doi.org/10.3390/ijns4040036 | [PMID: 27638987] |
Prenatal screening: | Yes (Regional) | Offered on a targeted, ad hoc basis. | [PMID: 19038079] |
Antenatal screening: | Yes (National) | Antenatal/preconceptional screening. | [PMID: 29751732] |
Haemoglobinopathies patient registry: | No | Data Information System for Hemoglobinopathies (DISH) developed by Children’s Hospital of Eastern Ontario to monitor disease-related complications and health outcomes. | |
Rare disease patient registry: | No | Plans for an Ontario-specific RD registry. From: CCSO Rare Diseases Working Group Report 2017 | |
Dedicated treatment centres: | Yes (Regional) | Clinics providing dedicated Sickle Cell or Thalassemia services in British Columbia, Alberta, Saskatchewan, Manitoba, Ontario, Quebec, Nova Scotia, Newfoundland . From: https://www.canhaem.org/ | |
Blood transfusion availability: | Yes (Regional) | Clinics providing blood transfusion support in British Columbia, Alberta, Saskatchewan, Manitoba, Ontario, Quebec, Nova Scotia, Newfoundland . From: https://www.canhaem.org/ | |
Iron chelation availability: | Yes (Regional) | Clinics providing dedicated Sickle Cell or Thalassemia services including iron chelation in British Columbia, Alberta, Saskatchewan, Manitoba, Ontario, Quebec, Nova Scotia, Newfoundland. From: https://www.canhaem.org/ | |
MRI facilities: | Yes (Regional) | Clinics providing dedicated Sickle Cell or Thalassemia services including iron overload monitoring with MRI in British Columbia, Alberta, Saskatchewan, Manitoba, Ontario, Quebec, Nova Scotia, Newfoundland. From: https://www.canhaem.org/ | |
Patient associations: | Yes (National) | E.g.: Thalassaemia Foundation of Canada; The Sickle Cell Disease Association of Canada |
Prevalence and incidence of major haemoglobinopathies in Canada
Haemoglobinopathy | Comment/Info | Reference | |
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Prevalence of β-thalassaemia carriers: | 0.5 % of the population | [PMID: 24672827] | |
Prevalence of sickle cell disease carriers: | 0.3 % of the population | [PMID: 24672827] | |
Prevalence of Hb E carriers: | 0.25 % of the population | From: Modell's Haemoglobinopathologist's Almanac. | |
Prevalence of Hb C carriers: | 0.097 % of the population | From: Modell's Haemoglobinopathologist's Almanac. | |
Expected incidence of β-thalassaemia: | 4 expected affected births/year | [PMID: 24672827] | |
Expected incidence of sickle cell disease: | 3 expected affected births/year | [PMID: 24672827] | |
Incidence of sickle cell disease: | 45 affected births/year | Median value estimated using statistical model and demographic data. | [PMID: 23103089] |
Known β-thalassaemia patients: | 300 patients | [PMID: 24672827] | |
Known sickle cell disease patients: | 4000 patients | Ranges between 3000 and 5000, the majority of whom reside in Ontario and Quebec. From: doi.org/10.3390/ijns4040036 |
Global Burden of Disease data for Canada
Migration data for Canada
Mutation frequencies in Canada
Organisations in Canada
A list of all organisations in Canada stored in the ITHANET database is shown below. For more information, click on the corresponding organisation name or visit the detailed ITHANET Organisations page
Name | Department | Organisation type |
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Hamilton Health Sciences | Hamilton Regional Laboratory Medicine Program | Research Center, Medical Center |
Microattributions
No microattibutions were provided for Canada. Please contact us, if you are willing to review existing information or provide new data.
To provide new epidemiological information and/or report mistakes, please register/log in first or use the Contact Us form.
Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.