Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
Search
General information for Sri Lanka
Sri Lanka |
|
---|
Haemoglobinopathy-specific healthcare policy information for Sri Lanka
Healthcare policy | Comment/Info | Reference | |
---|---|---|---|
Prevention programme: | Yes (National) | National thalassaemia screening programme for school children and young adults (premarital screening) has been in place since 2005. | [PMID: 31419232] |
Prenatal screening: | Yes (Regional) | Available since 2005 in the capital city of Colombo. | [PMID: 28397548] |
Antenatal screening: | No | From: Thalassaemia Reports 2012, TIF Pan-Asian Conference. | |
Haemoglobinopathies patient registry: | No | The Thalassaemia eRegistry is a pilot project run at Kurunegala and Anuradhapura Thalassaemia Centres. | |
Dedicated treatment centres: | Yes (Regional) | Four regional thalassaemia centres are located in the provinces with the highest burden of disease [From: WHO South-East Asia 2021 report, ISBN: 978-92-9022-851-6] | |
Blood transfusion availability: | Yes (National) | Blood Transfusion Services are free of charge for all patients in the country under the National Health Policy [From: WHO South-East Asia 2021 report, ISBN: 978-92-9022-851-6] | |
Iron chelation availability: | Yes (National) | Iron chelation is free of charge for all patients in the country under the National Health Policy [From: WHO South-East Asia 2021 report, ISBN: 978-92-9022-851-6] | |
Patient associations: | Yes (National) | e.g.: Thalassemia Circle Sri Lanka |
Prevalence and incidence of major haemoglobinopathies in Sri Lanka
Haemoglobinopathy | Comment/Info | Reference | |
---|---|---|---|
Prevalence of β-thalassaemia carriers: | 2.5 % of the population | [PMID: 27040959] | |
Prevalence of sickle cell disease carriers: | 1 % of the population | Less than 1%. From: Thalassaemia Reports 2012, TIF Pan-Asian Conference. | |
Prevalence of Hb E carriers: | 2.5 % of the population | [PMID: 27040959] | |
Expected incidence of β-thalassaemia: | 64 expected affected births/year | [PMID: 24672827] | |
Incidence of sickle cell disease: | 2 affected births/year | Median value estimated using statistical model and demographic data. | [PMID: 23103089] |
Known β-thalassaemia patients: | 3410 patients | [PMID: 24672827] |
Global Burden of Disease data for Sri Lanka
Migration data for Sri Lanka
Mutation frequencies in Sri Lanka
Overview (most frequent mutations with their observed average values and range)
β-locus
IVS I-5 (G>C): 57.05 % (43.8 % – 71.1 %) | IVS I-1 G>A: 14.69 % (2.6 % – 27 %) |
CD 26 GAG>AAG [Glu>Lys] (HbE): 14.22 % (1.5 % – 43.8 %) | CD 121 GAA>CAA [Glu>Gln] (Hb D-Punjab): 6.3 % (0.1 % – 12.5 %) |
Detailed mutation frequencies
Entry ID | Locus | Region | Ethnic Group | Population Type | Sample Size | Study period (from) | Study period (to) | Reference | Comments | |
---|---|---|---|---|---|---|---|---|---|---|
22821 | β-locus | Anuradhapura | Multi-ethnic | Patients | 250 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22822 | β-locus | Badulla | Multi-ethnic | Patients | 152 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22823 | β-locus | Chilaw | Multi-ethnic | Patients | 88 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22824 | β-locus | Colombo | Multi-ethnic | Patients | 66 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22825 | β-locus | Galle | Multi-ethnic | Patients | 8 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22826 | β-locus | Kandy | Multi-ethnic | Patients | 80 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22827 | β-locus | Kurunegala | Multi-ethnic | Patients | 580 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22828 | β-locus | Negombo | Multi-ethnic | Patients | 16 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22829 | β-locus | Country-wide | Multi-ethnic | Patients | 1240 | 2003 | 12752111 | Frequencies are shown for beta-globin gene mutations. Study samples were acquired from health clinics in eight major cities of Sri Lanka. The patient population comprised of Sinhalese, Muslims (Moors and Malaysian) and Tamils. | ||
22830 | β-locus | Country-wide | Sri Lankan | Carriers and Patients | 560 | 2001 | 11791873 | Frequencies are shown for beta-globin gene mutations. The majority of samples studied were patients. |
Organisations in Sri Lanka
Organisations in Sri Lanka are currently not available
Microattributions
No microattibutions were provided for Sri Lanka. Please contact us, if you are willing to review existing information or provide new data.
To provide new epidemiological information and/or report mistakes, please register/log in first or use the Contact Us form.
Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.