Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
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General information for Morocco
 Morocco |
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Haemoglobinopathy-specific healthcare policy information for Morocco
| Healthcare policy | Comment/Info | Reference | |
|---|---|---|---|
| Prevention programme: | No | From: 2nd MEGMA Conference Proceedings. | |
| SCD newborn screening: | No | [PMID: 32415570] | |
| Prenatal screening: | No | From: 2nd MEGMA Conference Proceedings. | |
| Haemoglobinopathies patient registry: | No | From: Journal of Public Health and Epidemiology Vol. 2(2), pp. 25-28 | |
| Rare disease patient registry: | No | http://africa-rare.org/ | |
| Dedicated treatment centres: | Yes (Regional) | E.g.: The Haemato-Oncology Service in the Avicennes Hospital, Rabat. | |
| Blood transfusion availability: | Yes (National) | Transfusion system consists of 16 regional blood transfusion centres, 13 blood banks and 24 hospital-based sites, all under the supervision of the National Blood Transfusion Centre. | [PMID: 22420379] |
| Iron chelation availability: | Yes (National) | Limited accessibility. | |
| Patient associations: | Yes (National) | E.g.: Association Marocaine de Thalassémie et Drépanocytose. | |
| Genetic counselling: | Yes (National) | Offered upon request. From: 2011 WHO Report WHO-EM/NCD/068/E. |
Prevalence and incidence of major haemoglobinopathies in Morocco
| Haemoglobinopathy | Comment/Info | Reference | |
|---|---|---|---|
| Prevalence of β-thalassaemia carriers: | 1.67 % of the population | [PMID: 24672827] | |
| Prevalence of sickle cell disease carriers: | 1.76 % of the population | [PMID: 24672827] | |
| Prevalence of α-thalassaemia carriers: | 0.96 % of the population | Estimated from a regional pilot NBS study (2015-2016). | [PMID: 31001551] |
| Prevalence of Hb C carriers: | 1.07 % of the population | [PMID: 21415987] | |
| Expected incidence of β-thalassaemia: | 51 expected affected births/year | [PMID: 24672827] | |
| Expected incidence of sickle cell disease: | 164 expected affected births/year | [PMID: 24672827] | |
| Incidence of sickle cell disease: | 40 affected births/year | Median value estimated using statistical model and demographic data. | [PMID: 23103089] |
| Known β-thalassaemia patients: | 375 patients | [PMID: 24672827] |
Global Burden of Disease data for Morocco
Migration data for Morocco
Mutation frequencies in Morocco
Overview (most frequent mutations with their observed average values and range)
β-locus
| CD 39 CAG>TAG [Gln>STOP]: 26.39 % (26.2 % – 26.58 %) | CD 8 (-AA): 11.76 % (9.6 % – 13.91 %) |
| CD 6 -A: 9.5 % (5.7 % – 13.3 %) | IVS I-6 (T>C): 8.53 % (3.16 % – 13.9 %) |
Detailed mutation frequencies
| Entry ID | Locus | Region | Ethnic Group | Population Type | Sample Size | Study period (from) | Study period (to) | Reference | Comments | |
|---|---|---|---|---|---|---|---|---|---|---|
| 23109 | β-locus | Country-wide | Moroccan | Carriers and Patients | 187 | 2004 | 15008262 | Frequencies are shown for beta-globin gene mutations. Study samples originated from all over Morocco and were collected from hospitals at Casablanca and Rabat. . | ||
| 23110 | β-locus | Country-wide | Moroccan | Carriers and Patients | 158 | 2008 | 18976160 | Frequencies are shown for beta-globin gene mutations. Study samples originated from all over Morocco, and more than a half were homozygotes. |
Organisations in Morocco
Organisations in Morocco are currently not available
Microattributions
No microattibutions were provided for Morocco. Please contact us, if you are willing to review existing information or provide new data.
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Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.