Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
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General information for Maldives
Maldives |
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Haemoglobinopathy-specific healthcare policy information for Maldives
Healthcare policy | Comment/Info | Reference | |
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Prevention programme: | Yes (National) | The Thalassaemia prevention law enacted in 2012 mandates population-based premarital carrier screening. | [PMID: 27393346] |
SCD newborn screening: | No | [PMID: 24921462] | |
Prenatal screening: | Yes (National) | [PMID: 27040959] | |
Antenatal screening: | Yes (National) | [PMID: 24921462] | |
Haemoglobinopathies patient registry: | Yes (National) | National Thalassaemia Registry was established in 1993 & [Thalassaemia Reports 2014, WHO Mission, The Maldives] | [PMID: 22109823] |
Dedicated treatment centres: | Yes (National) | From: Thalassaemia Reports 2012, TIF Pan-Asian Conference. | |
Blood transfusion availability: | Yes (National) | All patients with haemoglobinopathies registered at Maldivian Blood Services can get free services [From: WHO South-East Asia 2021 report, ISBN: 978-92-9022-851-6] | |
Iron chelation availability: | Yes (National) | [PMID: 27040959] | |
Patient associations: | Yes (National) | E.g.: Maldivian Thalassaemia Society. | |
Genetic counselling: | Yes (National) | As part of the prevention programme. | [PMID: 27393346] |
Prevalence and incidence of major haemoglobinopathies in Maldives
Haemoglobinopathy | Comment/Info | Reference | |
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Prevalence of β-thalassaemia carriers: | 18 % of the population | [PMID: 27040959] | |
Prevalence of sickle cell disease carriers: | 0.13 % of the population | From: Thalassaemia Reports 2014, WHO Mission, The Maldives. | |
Prevalence of α-thalassaemia carriers: | 2.1 % of the population | From: Thalassaemia Reports 2014, WHO Mission, The Maldives. | |
Prevalence of Hb E carriers: | 0.9 % of the population | [PMID: 27040959] | |
Expected incidence of β-thalassaemia: | 54 expected affected births/year | [PMID: 24672827] | |
Incidence of β-thalassaemia: | 28 affected births/year | [PMID: 27393346] | |
Known β-thalassaemia patients: | 574 patients | [PMID: 24672827] |
Global Burden of Disease data for Maldives
Migration data for Maldives
Mutation frequencies in Maldives
Overview (most frequent mutations with their observed average values and range)
β-locus
IVS I-5 (G>C): 74.3 % | CD 30 (G>C) or IVS I (-1) AGG>ACG (Arg>Thr) (Hb Monroe): 15.4 % |
IVS I-1 G>A: 9 % | CD 41/42 (-CTTT): 1.3 % |
Detailed mutation frequencies
Entry ID | Locus | Region | Ethnic Group | Population Type | Sample Size | Study period (from) | Study period (to) | Reference | Comments | |
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23112 | β-locus | Country-wide | Maldivian | Patients | 78 | 1998 | 9576331 | Frequencies are shown for beta-globin gene mutations. Study samples were acquired from the Central Hospital of Malé. |
Organisations in Maldives
Organisations in Maldives are currently not available
Microattributions
No microattibutions were provided for Maldives. Please contact us, if you are willing to review existing information or provide new data.
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Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.