Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
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General information for Oman
Oman |
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Haemoglobinopathy-specific healthcare policy information for Oman
Healthcare policy | Comment/Info | Reference | |
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Prevention programme: | Yes (National) | [PMID: 23224852] | |
SCD newborn screening: | Yes (National) | SS-Hb is included in the national NBS program. | [PMID: 19606054] |
Prenatal screening: | No | [PMID: 25677748] | |
Haemoglobinopathies patient registry: | Yes (National) | National Register of Symptomatic Hemoglobinopathies. | [PMID: 11360093] |
Dedicated treatment centres: | Yes (National) | From: PGPR, Global Sickle Cell Disease Network. | |
Blood transfusion availability: | Yes (National) | [PMID: 20376265] | |
MRI facilities: | Yes (National) | From: PGPR, Global Sickle Cell Disease Network. | |
Patient associations: | Yes (National) | E.g.: Oman Hereditary Blood Disorder Association (OHBDA). | |
Genetic counselling: | Yes (National) | [PMID: 23821042] |
Prevalence and incidence of major haemoglobinopathies in Oman
Haemoglobinopathy | Comment/Info | Reference | |
---|---|---|---|
Prevalence of β-thalassaemia carriers: | 3.1 % of the population | [PMID: 24672827] | |
Prevalence of sickle cell disease carriers: | 5.7 % of the population | [PMID: 24672827] | |
Prevalence of α-thalassaemia carriers: | 48.5 % of the population | [PMID: 20353348] | |
Expected incidence of β-thalassaemia: | 16 expected affected births/year | [PMID: 24672827] | |
Expected incidence of sickle cell disease: | 105 expected affected births/year | [PMID: 24672827] | |
Known β-thalassaemia patients: | 591 patients | [PMID: 24672827] | |
Known sickle cell disease patients: | 4704 patients | [PMID: 24672827] |
Global Burden of Disease data for Oman
Migration data for Oman
Mutation frequencies in Oman
Overview (most frequent mutations with their observed average values and range)
β-locus
IVS I-5 (G>C): 44.7 % (25 % – 61.6 %) | -71 C>T: 12 % (7.9 % – 17.2 %) |
CD 44 -C: 10.67 % (1.69 % – 37.5 %) | CD 58 CCT>CAT [Pro>His] (Hb Sheffield): 8.7 % (2.3 % – 25 %) |
Detailed mutation frequencies
Entry ID | Locus | Region | Ethnic Group | Population Type | Sample Size | Study period (from) | Study period (to) | Reference | Comments | |
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23382 | β-locus | Country-wide | Omani | Patients | 198 | 1998 | 9668567 | Frequencies are shown for beta-globin gene mutations. | ||
23383 | β-locus | Country-wide | Omani | Carriers and Patients | 517 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations from both carriers and patients. Study samples were acquired from the Ministry of Health Hospitals throughout the country. | ||
23384 | β-locus | Musandam | Omani | Carriers and Patients | 59 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations. | ||
23385 | β-locus | Batinah | Omani | Carriers and Patients | 93 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations from both carriers and patients livign in Al Batnah (North and South). | ||
23386 | β-locus | Muscat | Omani | Carriers and Patients | 264 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations from both carriers and patients. | ||
23387 | β-locus | Dhahira | Omani | Carriers and Patients | 20 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations from both carriers and patients. | ||
23388 | β-locus | Dakhiliya | Omani | Carriers and Patients | 29 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations from both carriers and patients. | ||
23389 | β-locus | Sharqiya | Omani | Carriers and Patients | 40 | 2015 | 25677748 | Frequencies are shown for beta-globin gene mutations from both carriers and patients living in Al Sharqiyah (North and South). |
Organisations in Oman
Organisations in Oman are currently not available
Microattributions
No microattibutions were provided for Oman. Please contact us, if you are willing to review existing information or provide new data.
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Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.