Welcome to IthaMaps

IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.

IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge

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  General information for Serbia


Serbia
Continent: Europe
Capital: Belgrade
Population: 7344847
Area (in sq km): 88361.0

Haemoglobinopathy-specific healthcare policy information for Serbia

Healthcare policyComment/InfoReference
SCD newborn screening: NoSCD is not included in the neonatal screening panel.[PMID: 33808002]
Prenatal screening: Yes (National)[PMID: 15870487]
Haemoglobinopathies patient registry: NoFrom: TIF_THALIA Report 2021
MRI facilities: NoFrom: TIF_THALIA Report 2021

  Prevalence and incidence of major haemoglobinopathies in Serbia

HaemoglobinopathyComment/InfoReference
Prevalence of β-thalassaemia carriers: 1.2 % of the population[PMID: 24672827]
Expected incidence of β-thalassaemia: 2 expected affected births/year[PMID: 24672827]
Incidence of sickle cell disease: 10 affected births/yearMedian value estimated using statistical model and demographic data.[PMID: 23103089]

  Global Burden of Disease data for Serbia

  Migration data for Serbia

Mutation frequencies in Serbia

 Overview (most frequent mutations with their observed average values and range)

 β-locus

Hb Lepore-Boston-Washington: 29.6 % (26.2 % – 33 %)CD 39 CAG>TAG [Gln>STOP]: 19.1 % (16.2 % – 22 %)
IVS II-745 C>G: 16.4 % (12 % – 20.8 %)IVS I-110 G>A: 15.8 % (14.6 % – 17 %)

 Detailed mutation frequencies

Entry IDLocusRegionEthnic GroupPopulation TypeSample SizeStudy period (from)Study period (to)ReferenceComments
23214β-locusBelgradeMutli-ethnicCarriers731998200515870487Frequencies are shown for beta-globin gene mutations from both carriers and patients. Study samples were acquired from health clinics in Belgrade and were of Serbian or Montenegrin descent. Three of these were beta-thalassaemia patients.
23215β-locusBelgradeSerbsCarriers1301998201020854122Frequencies are shown for beta-globin gene mutations from both carriers and patients. Study samples were acquired from health clinics in Belgrade and were Serbs, Slavs by origin. Three of these were beta-thalassaemia patients.

  Organisations in Serbia

Organisations in Serbia are currently not available

 Microattributions

No microattibutions were provided for Serbia. Please contact us, if you are willing to review existing information or provide new data.

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Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.

Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaMaps are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.