Welcome to IthaMaps
IthaMaps is a global epidemiology database of heamoglobinopathies, illustrating published data on a dynamic global to regional map. Country-specific information on haemoglobinopathy-related policies, prevalence, incidence and overall disease burden is given, including relative allele frequencies of specific globin mutations in each country and/or region, dynamically linked to corresponding IthaGenes entries.
IthaMaps content was supported by partnership with the HVP Global Globin 2020 Challenge
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General information for Vietnam
 Vietnam |
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Haemoglobinopathy-specific healthcare policy information for Vietnam
| Healthcare policy | Comment/Info | Reference | |
|---|---|---|---|
| Prevention programme: | Yes (Regional) | In Hoa Binh province. From: 11th Asia Pacific Conference on Human Genetics. | |
| SCD newborn screening: | Yes (National) | Bionet NBS Center screens for haemoglobinopathies, incl. SCD, across 45 provinces. | [PMID: 33072985] |
| Prenatal screening: | Yes (Regional) | It is offered at three hospitals [PMCID: PMC4563497] | |
| Haemoglobinopathies patient registry: | No | From: TIF report on South East Asian Nations, Aug. 2013. | |
| Rare disease patient registry: | No | [PMID: 27484654] | |
| Dedicated treatment centres: | Yes (Regional) | E.g.: One thalassaemia centre at the National Institute of Haematology and Blood Transfusion. From: 11th Asia Pacific Conference on Human Genetics. | |
| Blood transfusion availability: | Yes (National) | E.g.: National Institute of Haematology and Blood Transfusion. From: 11th Asia Pacific Conference on Human Genetics. | |
| Iron chelation availability: | Yes (Regional) | Iron chelators (DFO, DFP, DFX) available only in large central hospitals but are limited in supply. From: Thalassaemia Reports 2012, TIF Pan-Asian Conference. | |
| MRI facilities: | No | From: 11th Asia Pacific Conference on Human Genetics. | |
| Patient associations: | Yes (National) | E.g.: Vietnamese Thalassaemia Association. | |
| Genetic counselling: | Yes (Regional) | It is offered at three hospitals [PMCID: PMC4563497] |
Prevalence and incidence of major haemoglobinopathies in Vietnam
| Haemoglobinopathy | Comment/Info | Reference | |
|---|---|---|---|
| Prevalence of β-thalassaemia carriers: | 2.6 % of the population | 1.49% in Kinh, 10.7% in Muong, 11% in Tay ethnic groups. From: 11th Asia Pacific Conference on Human Genetics. | [PMID: 27040959] |
| Prevalence of α-thalassaemia carriers: | 5 % of the population | TIF report on South East Asian Nations, Aug. 2013 | |
| Prevalence of Hb E carriers: | 1 % of the population | 1.24% in Kinh, 11.7% in Muong, 1% in Tay ethnic groups. From: 11th Asia Pacific Conference on Human Genetics. | [PMID: 27040959] |
| Expected incidence of β-thalassaemia: | 424 expected affected births/year | [PMID: 24672827] | |
| Incidence of β-thalassaemia: | 430 affected births/year | ||
| Known β-thalassaemia patients: | 1000 patients | [PMID: 24672827] |
Global Burden of Disease data for Vietnam
Migration data for Vietnam
Mutation frequencies in Vietnam
Overview (most frequent mutations with their observed average values and range)
β-locus
| CD 26 GAG>AAG [Glu>Lys] (HbE): 33.53 % (29.2 % – 37 %) | CD 41/42 (-CTTT): 24.85 % (18.8 % – 35.3 %) |
| CD 17 AAG>TAG [Lys>STOP]: 24.2 % (19.95 % – 30 %) | IVS I-1 (G>T): 5.72 % (2.85 % – 8.3 %) |
Detailed mutation frequencies
| Entry ID | Locus | Region | Ethnic Group | Population Type | Sample Size | Study period (from) | Study period (to) | Reference | Comments | |
|---|---|---|---|---|---|---|---|---|---|---|
| 23635 | β-locus | Ho Chi Minh | Vietnamese (Kinh) | Carriers and Patients | 737 | 2012 | 2020 | 35023007 | Frequencies are shown for beta-globin gene mutations. Samples were collected at the Blood Transfusion and Hematology Hospital at Ho Chi Minh City, Southern Vietnam, from Febr. 2012 to April 2020. They belonged mainly to Kinh people, followed by Chinese, Khmer and other ethnic groups. The majority were carriers (92%). Mutation analysis was performed by sequencing the entire HBB gene. | |
| 23636 | β-locus | Hanoi | Vietnamese | Carriers and Patients | 750 | 2018 | 29493329 | Frequencies are shown for four common beta-globin gene mutations and were calculated by Ithanet. Samples were collected at the National Institute of Hematology and Blood Transfusion, Cau Giay, Hanoi. | ||
| 23637 | β-locus | Hanoi | Vietnamese | Patients | 46 | 2000 | 10870880 | Frequencies are shown for beta-globin gene mutations. Study samples were acquired from the Institute for the Protection of Children's Health, Hanoi, North Vietnam, and were mainly of the Kinh ethnic group. | ||
| 23638 | β-locus | Ho Chi Minh | Vietnamese | Patients | 68 | 2002 | 12353305 | Frequencies are shown for beta-globin gene mutations. Study samples were acquired from the Blood Transfusion and Haematology Centre, Ho Chi Minh City, South Vietnam, and were mainly of the Kinh ethnic group. | ||
| 23639 | β-locus | Thua Thien Hue | Kinh | Carriers and Patients | 48 | 2017 | 28671035 | Frequencies are shown for beta-globin gene mutations. Study samples were acquired from the Hue Central Hospital, Hue, Central Vietnam, and were mainly of the Kinh ethnicity with one patient of the Ta Oi and two of the Pako ethnicities. The majority were patients (22 out of 26 samples). |
Organisations in Vietnam
Organisations in Vietnam are currently not available
Microattributions
No microattibutions were provided for Vietnam. Please contact us, if you are willing to review existing information or provide new data.
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Important Note: The relative allele frequencies presented in IthaMaps are not calculated by ITHANET, but they are extracted from the corresponding publications. ITHANET is not responsible for any mistakes in the data. Please use this information with caution! We encourage scientists that have more detailed or updated epidemiological information to contact us.
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