GeneID: 410
Names
Common Name: | WWOX | Type: | Gene |
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Chromosome: | 16 (NC_000016.10) | Locus: | NG_011698.1 (WWOX) |
HUGO Symbol: | WWOX | Full Name: | WW domain containing oxidoreductase |
Exons: | 9 | Introns: | 8 |
Description:
The WWOX gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. Acts as a tumor suppressor and plays a role in apoptosis. Associated with haematopoietic malignancies. Genetic variance in WWOX associated with F-cell levels in sickle cell anaemia.
Synonyms: FOR , WOX1 , EIEE28 , FRA16D , SCAR12 , HHCMA56 , PRO0128 , SDR41C1 , D16S432E
Comments:
N/A
Number of entries/variants: 1
Sequence Viewer
Publications / Origin
- Bhatnagar P, Purvis S, Barron-Casella E, DeBaun MR, Casella JF, Arking DE, Keefer JR, Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients., J. Hum. Genet. , 56(4), 316-23, 2011 PubMed
A/A | Date | Curator(s) | Comments |
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1 | 2020-10-15 14:56:44 | The IthaGenes Curation Team | Created |